RESUMEN
At present, coronavirus disease-19 (COVID-19) caused by novel coronavirus (SARS-CoV-2) has been spreading around the world, but no specific therapeutic drug or vaccine has been developed for the virus. By collecting the latest literature and searching related database websites, the biological characteristics and main targets of SARS-CoV-2, the clinical therapeu tic drugs and the latest drug research were reviewed to provide information for clinical treatment and provide reference for the research and development of new drugs against SARS-CoV-2.Copyright © 2020 Publication Centre of Anhui Medical University. All rights reserved.
Asunto(s)
Antiinflamatorios/uso terapéutico , Antivirales/uso terapéutico , Berberina/uso terapéutico , Tratamiento Farmacológico de COVID-19 , COVID-19/sangre , Mediadores de Inflamación/sangre , Síndrome de Liberación de Citoquinas/sangre , Síndrome de Liberación de Citoquinas/tratamiento farmacológico , Humanos , Estudios Prospectivos , SARS-CoV-2RESUMEN
At present, coronavirus disease-19 (COVID-19) caused by novel coronavirus (SARS-CoV-2) has been spreading around the world, but no specific therapeutic drug or vaccine has been developed for the virus. By collecting the latest literature and searching related database websites, the biological charac¬teristics and main targets of SARS-CoV-2, the clinical therapeu¬ tic drugs and the latest drug research were reviewed to provide information for clinical treatment and provide reference for the research and development of new drugs against SARS-CoV-2.
RESUMEN
The purpose of this study was to retrospectively analyze the clinical significance of serum total protein, serum globulin, serum albumin and white globular ratio of patients with coronavirus disease 2019 upon admission. Enrolled 82 cases of coronavirus disease 2019 patients admitted to Wuhan Seventh Hospital, Hubei Province, including 34 cases of ordinary patients, 32 cases of severe patients, and 16 cases of critical patients. The age, gender, chronic underlying disease, total serum protein, serum globulin, serum albumin and white globular ratio in 3 groups were collected. The blood routine indicators of each group of patients were tested and analyzed, and the inflammation indicators C-reactive protein and procalcitonin on the 1st, 3rd and 7th d of treatment were compared. The experimental results showed that compared with ordinary patients and severe patients, the nutritional loss of critically ill patients was obvious. In clinical treatment, the decrease of albumin should be paid close attention and corrected in time.